Ostomyland's Wicked Wiki: Virtual Colonoscopy Research

Most recent edit on 2007-11-10 08:52:48 by KathyFromEngland [Restored to Original Version by Kathy]

Additions:
Optical colonoscopy (OC) and flexible sigmoidscopy (FS) have been the primary screening tools for the last few decades but are associated with complications ?C from abdominal pain to life-threatening bowel perforation and bleeding. Virtual colonoscopy, or CT colonography (CTC), has arisen as a potentially effective CRC screening tool. Using x-rays and imaging software to develop two- and three-dimensional images of the gastrointestinal tract, it has fewer adverse effects and is better tolerated by patients. Recent studies using new methods have demonstrated that the test is very sensitive for CRC and could be an effective screening option for patients.

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Optical colonoscopy (OC) and flexible sigmoidscopy (FS) have been the primary screening tools for the last few decades but are associated with complications ¨C from abdominal pain to life-threatening bowel perforation and bleeding. Virtual colonoscopy, or CT colonography (CTC), has arisen as a potentially effective CRC screening tool. Using x-rays and imaging software to develop two- and three-dimensional images of the gastrointestinal tract, it has fewer adverse effects and is better tolerated by patients. Recent studies using new methods have demonstrated that the test is very sensitive for CRC and could be an effective screening option for patients.

Edited on 2007-11-10 08:44:13 by LetotRocdo

Additions:
orzelrelre
Optical colonoscopy (OC) and flexible sigmoidscopy (FS) have been the primary screening tools for the last few decades but are associated with complications ¨C from abdominal pain to life-threatening bowel perforation and bleeding. Virtual colonoscopy, or CT colonography (CTC), has arisen as a potentially effective CRC screening tool. Using x-rays and imaging software to develop two- and three-dimensional images of the gastrointestinal tract, it has fewer adverse effects and is better tolerated by patients. Recent studies using new methods have demonstrated that the test is very sensitive for CRC and could be an effective screening option for patients.

Deletions:
Optical colonoscopy (OC) and flexible sigmoidscopy (FS) have been the primary screening tools for the last few decades but are associated with complications ?C from abdominal pain to life-threatening bowel perforation and bleeding. Virtual colonoscopy, or CT colonography (CTC), has arisen as a potentially effective CRC screening tool. Using x-rays and imaging software to develop two- and three-dimensional images of the gastrointestinal tract, it has fewer adverse effects and is better tolerated by patients. Recent studies using new methods have demonstrated that the test is very sensitive for CRC and could be an effective screening option for patients.

Edited on 2007-05-09 09:34:35 by KathyFromEngland

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~*Avantis Medical Systems Announces FDA 510(k) Approval For The Third Eye Retroscope

Avantis Medical Systems Announces FDA 510(k) Approval For The Third Eye Retroscope
04 May 2007
Today Avantis Medical Systems, Inc. announced that it has received FDA clearance to market its Third Eye(TM) Retroscope(TM) Auxiliary Endoscopy System.
The Third Eye Retroscope is an imaging device that is used during colonoscopy to provide an additional view that can reveal polyps, cancers and other lesions that might be missed during a standard colonoscopy procedure.
Although colonoscopy is widely regarded as the "gold standard" for detection of abnormalities in the colon, research has shown that a significant number of polyps and cancers may be missed during colonoscopy. (1,2) In about 2/3 of cases where abnormalities are missed, it is because they lie behind flexures (tight turns) or behind folds in the colon wall that hide them from the forward-viewing colonoscope.(3)
Developed by Avantis Medical Systems, Inc. of Sunnyvale, Calif., the Third Eye Retroscope is passed through the instrument channel of a standard colonoscope until it extends beyond its tip. As it emerges, the device automatically turns around 180 degrees to aim back toward the tip of the colonoscope. Then, as the colonoscope is withdrawn, the Third Eye follows along to provide a continuous retrograde view of the colon. This retrograde view complements the forward view of the colonoscope and may reveal abnormalities that are hidden behind folds and flexures.
A laboratory bench study(4) found that the device dramatically improved the ability of endoscopists to detect simulated polyps in anatomical models, and a pilot study demonstrated the feasibility of the device for use in humans.(5) A larger clinical study to evaluate efficacy is currently in progress.
According to David Watts, MD, a co-founder of the company and member of the Avantis Scientific Advisory Board, "This is the most exciting new development for colorectal cancer screening in a decade."
Fred Seddiqui, Avantis' CEO, said, "We are delighted to have received FDA approval under the 510(k) process. It is a great step forward for the Third Eye Retroscope. There is growing recognition of the need for new technology to improve the detection rate during colonoscopy, and we believe the Third Eye offers the ideal solution."
"This cutting-edge technology is complementary to the existing infrastructure," said Dr. Watts. "Because the Third Eye works in conjunction with a standard colonoscope, it simply takes the best existing technology and makes it even better. That means facilities don't need to make major capital outlays to replace existing equipment, and endoscopists have to make only minor adjustments to the techniques that they've used successfully for years."
http://www.medilexicon.com/medicalnews.php?newsid=69825∞

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Edited on 2007-04-27 08:20:57 by KathyFromEngland

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~*Virtual Colonoscopy Most Cost-Effective Colon Cancer Screening Test

Virtual Colonoscopy Most Cost-Effective Colon Cancer Screening Test
26 Apr 2007
A new study says targeting smaller lesions does little to significantly reduce the incidence of colorectal cancer (CRC) and, in fact, results in extremely high financial costs and a large proportion of adverse events. Published in the June 1, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society, a cost-benefit analysis study says the low malignancy rate among so-called diminutive polyps gives virtual colonoscopy with removal of lesions 6 mm or greater the best estimated value per life year gained and with fewer complications.
Effective screening through increased use of any of several available tests is the key to reducing deaths from colorectal cancer, the third leading cause of cancer death in both men and women. Despite the availability of effective screening tests, screening rates remain low and CRC-related deaths remain high.
Optical colonoscopy (OC) and flexible sigmoidscopy (FS) have been the primary screening tools for the last few decades but are associated with complications ?C from abdominal pain to life-threatening bowel perforation and bleeding. Virtual colonoscopy, or CT colonography (CTC), has arisen as a potentially effective CRC screening tool. Using x-rays and imaging software to develop two- and three-dimensional images of the gastrointestinal tract, it has fewer adverse effects and is better tolerated by patients. Recent studies using new methods have demonstrated that the test is very sensitive for CRC and could be an effective screening option for patients.
Previous cost-benefit analysis studies comparing OC and CTC (with OC referral for all polyps of any size) have estimated that OC is more cost effective. However, these studies ignore current CTC guidelines that recommend only reporting polyps greater than 5 mm. Dr. Perry Pickhardt, a radiologist from the University of Wisconsin, collaborated with Dr. Cesare Hassan, a gastroenterologist from Rome, and colleagues to conduct a cost-benefit analysis comparing CTC with and without a 6-mm polyp size threshold, OC and FS.
In this model of 100,000 persons over 50 years old, CTC with OC follow-up of polyps greater than 5 mm was the most cost-effective screening test. According to cost per life-year gained calculations, CTC with a 6-mm threshold for follow-up cost only $4,361 while OC cost $9,180 per life-year gained. CTC with no polyp size threshold cost $7,138, and FS cost $7,407 per life-year gained.
The incremental costs of working-up lesions smaller than 6 mm at CTC resulted in a significant $118,440 per additional life-year gained and accounted for more than half of all OC procedures. Moreover, working up these small, almost always benign polyps with OC caused considerable complications. The study found almost half of all OC-related complications were attributable to work-up of diminutive lesions. Furthermore, targeting these lesions did not improve screening efficacy, reducing CRC incidence by only 1.3 percent.
The authors say the data support "CTC with nonreporting of diminutive lesions" to be "the most cost-effective and safest screening option available." "Providing additional effective yet distinct screening options like CTC could encourage more adults to undergo screening," conclude the authors, and consequently "increase overall compliance with screening" for CRC.
http://www.medilexicon.com/medicalnews.php?newsid=68657∞

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